Mist inhaler might increase the risk of death ?

what is a mist inhaler ?

Mist inhaler is one of the several types of devices for taking COPD medication . Recently there was lot of criticism in the press about using mist inhalers

What are the popular brands ?

Sprivia and Primatene are popular brands that produce these devices

Is it dangerous to use them ?

Recent publications indicate that tiotropium dosage may lead to dangerous situation and increase the risk of death. They tested on 6500 patients and found that there was 52 percent increased risk of death when using triotopium compared to placebo

“What we think is going on is that the mist inhaler is delivering a higher concentration of tiotropium than it should be and that may be increasing the risk of death,” said Sonal Singh, an assistant professor of general internal medicine at the Johns Hopkins University School of Medicine and the lead author of the study.


Primatene inhalers:

Primatene mist is available as 15mL and refills . It is one of the commonly used over the counter mist inhaler.


More info on primatene usage from its label:


How to use the primatene mist inhaler ?


Sprivia inhaler:

Spiriva Respimat (tiotropium) mist inhaler got negative feedback as mentioned above .Boehringer contested the publication results